Can Suboxone Make You Sick?

June 26, 2024

Explore how Suboxone can affect you, from common side effects to potential risks. Can it make you sick? Find out here.

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Understanding Suboxone Use

Before delving into the specifics of whether Suboxone can make you sick, it's essential to understand what Suboxone is and its purpose.

What is Suboxone?

Suboxone is a medication that contains two active ingredients: buprenorphine and naloxone. Buprenorphine is a long-acting partial opioid agonist, meaning it weakly activates the opioid receptors without causing significant intoxication in individuals with opioid tolerance. On the other hand, naloxone is an opioid antagonist that can quickly reverse the effects of opioids. This combination of ingredients helps treat opioid use disorder.

Purpose of Suboxone

The primary purpose of Suboxone is to treat opioid use disorder, a chronic condition where individuals have compulsive, prolonged self-administration of opioid substances that are used for neither medical purposes nor their intended use.

Suboxone works by occupying the brain's opioid receptors, therefore blocking the effect of other opioids. This action helps manage the symptoms of opioid withdrawal and reduces cravings, thereby promoting recovery. However, while Suboxone can be an effective tool in managing opioid use disorder, it's important to note that it can also cause side effects, some of which might make users feel ill. These potential side effects will be discussed further in the following sections.

In the landscape of medication-assisted treatment, Suboxone has limited alternatives, with methadone being the primary competitor. However, methadone is a full opioid agonist with a higher abuse potential than Suboxone.

Understanding the purpose and function of Suboxone is key to addressing the question, "Can Suboxone make you sick?" The subsequent sections will delve into the common side effects of Suboxone, risks and concerns, administration and effects, interactions and precautions, and how to manage Suboxone treatment.

Common Side Effects of Suboxone

Suboxone, a medication used in the treatment of opioid addiction, is generally well-tolerated by most people. However, like any medication, Suboxone can cause side effects. These side effects can range from mild and relatively common, to severe and infrequent. It's important to be aware of these potential side effects in order to recognize and address them promptly.

Mild Side Effects

Common, mild side effects of Suboxone include constipation, headache, nausea, and insomnia [4]. These are generally manageable and often lessen with time as the body adjusts to the medication. However, if they persist or become bothersome, seeking medical advice is recommended.

Here is a list of the most common mild side effects:

  • Constipation
  • Headache
  • Nausea
  • Insomnia

It's also worth noting that Suboxone can cause relaxation that some individuals might become attached to, potentially leading to addiction or drug relapse [3].

Severe Side Effects

While severe side effects of Suboxone are less common, they can occur and require immediate medical attention. These can include orthostatic hypotension (low blood pressure when standing up), allergic reactions, and overdose symptoms like shallow breathing and extreme drowsiness.

One particularly serious side effect is respiratory depression, which can lead to shallow or slow breathing, resulting in a lack of oxygen in the body. This side effect occurs in 1-10% of patients and requires immediate medical help.

Here is a list of the most common severe side effects:

  • Orthostatic hypotension
  • Allergic reactions
  • Overdose symptoms (shallow breathing, extreme drowsiness)
  • Respiratory depression

It's important to remember that while these side effects can be concerning, they are not common, and Suboxone is a crucial medication in the fight against opioid addiction. However, knowing the potential side effects and being vigilant can ensure that any issues are addressed promptly and appropriately.

Risks and Concerns

While Suboxone is often used in the treatment of opioid addiction, it comes with its own risks and concerns. It's crucial that individuals using this medication understand its potential for addiction, risks of overdose, and long-term effects.

Addiction Potential

Suboxone is a medication that can be beneficial in the management of opioid addiction, but it's not without its own risks. Users may become attached to the relaxation it causes, potentially leading to addiction or even drug relapse, according to the American Addiction Centers. Furthermore, taking Suboxone long-term for opioid dependence can lead to both physical and psychological dependence, increasing the risk of misuse and addiction Healthline.

Overdose Risks

Overdose is another serious concern associated with Suboxone use. One of the more severe side effects of Suboxone is respiratory depression, which can occur in 1-10% of patients American Addiction Centers. This condition can lead to shallow or slow breathing, resulting in a lack of oxygen in the body. Users experiencing this side effect should seek immediate medical help.

Long-Term Effects

Long-term use of Suboxone can have significant effects on an individual's health and wellbeing. Chronic use of this medication can lead to constipation, headaches, nausea, and insomnia Healthline. Additionally, use during pregnancy can cause neonatal opioid withdrawal syndrome in babies, and the drug can pass into breast milk. This requires close monitoring of breastfed infants for serious side effects Healthline.

It's crucial that individuals considering or currently using Suboxone for the treatment of opioid dependence are fully informed about these potential risks and concerns. Medical advice should always be sought before starting or stopping any medication, including Suboxone. If the question "can Suboxone make you sick?" is on your mind, the answer is yes, but with the right monitoring and professional guidance, the benefits of this medication can outweigh the risks for many individuals.

Suboxone Administration and Effects

When considering the question, "can suboxone make you sick?" it's important to understand how Suboxone is administered and the potential effects it can produce. This includes the guidelines for dosage, the duration of effects, and the withdrawal process.

Dosage Guidelines

Suboxone treatment is administered in four distinct phases: induction, stabilization, maintenance, and taper. It's crucial to adhere to the guidelines for each phase to ensure the treatment's effectiveness and minimize any adverse effects. Most people experience buprenorphine’s effects for almost the entire day, so sublingual Suboxone is typically taken about once per day. However, some individuals may be advised to take it every other day, divide the dose into smaller doses, or take it two to three times daily based on individual needs [1].

Duration of Effects

The length of time Suboxone stays in the system depends on various factors, including dosage, metabolism, and individual health factors. Generally, it can take 9 to 14 days to be fully flushed out after the last dose. The effects of Suboxone typically last up to three days, but doctors recommend daily intake. Due to differences in metabolism, the duration of Suboxone's effects can vary from person to person, making it crucial to follow the doctor's instructions.

Withdrawal Process

Abrupt discontinuation of Suboxone can lead to acute withdrawal symptoms that could last up to a month, significantly longer than withdrawal symptoms from substances like heroin, which typically last around a week. To minimize the severity of withdrawal symptoms and make the process more manageable, it's recommended to slowly taper off Suboxone over weeks to months under the guidance of a medical provider. This approach can significantly reduce the severity of withdrawal during the Suboxone tapering process, making the transition easier and more comfortable for the patient [1].

Understanding how Suboxone is administered, its potential effects, and the withdrawal process can provide valuable insights and answer questions like "can suboxone make you sick?". It's always important to seek professional medical advice when considering or undergoing treatment with Suboxone or any other medication.

Suboxone Interactions and Precautions

In the context of answering the question 'can suboxone make you sick?', it is crucial to understand how Suboxone interacts with other substances and the precautions one must take while using it. Suboxone, a medication containing buprenorphine and naloxone, is used to treat opioid use disorder [2]. However, misusing Suboxone or combining it with certain substances can lead to adverse effects.

Mixing with Alcohol

Suboxone should not be taken with alcohol. Combining these substances can increase the risk of dangerous side effects such as severe sedation, breathing problems, coma, and even death [6]. This is due to the fact that both substances can depress the central nervous system, slowing breathing and potentially leading to overdose or death.

Other Medication Interactions

Suboxone can also interact with other medications, potentially leading to serious complications. For example, when taken with other opioids, the naloxone in Suboxone can quickly reverse the effects of the opioids, which can make people sick. Additionally, the misuse of Suboxone by taking it at too high of a dose, without a prescription, or in any other way than intended can lead to addiction and overdose, as it is an opioid itself.

Pregnancy and Breastfeeding

Special considerations should be taken for people who are pregnant or breastfeeding. Suboxone use during pregnancy can cause neonatal opioid withdrawal syndrome in babies. This is a condition that causes a newborn to experience withdrawal symptoms after birth due to exposure to opioids while in the womb. Additionally, Suboxone can pass into breast milk and may cause serious side effects in a breastfeeding infant. As such, close monitoring of breastfed infants is required if the mother is taking Suboxone [4].

In all cases, it's important to use Suboxone under the supervision of a healthcare professional. This medication is a controlled substance classified as a Schedule III prescription drug, indicating its potential for physical or psychological dependence and risk of misuse. Special rules exist for its prescription and dispensing, and it should be used exactly as directed by a healthcare professional.

Managing Suboxone Treatment

The proper management of Suboxone treatment is crucial for ensuring its effectiveness and minimizing potential side effects. This involves understanding the tapering process, recognizing acute withdrawal symptoms, and seeking regular medical guidance.

Tapering Process

Suboxone treatment is typically administered in four phases: induction, stabilization, maintenance, and taper. The tapering process refers to gradually reducing the dosage of Suboxone over time to minimize withdrawal symptoms and potential dependence on the medication. It's important to note that abruptly discontinuing Suboxone can lead to acute withdrawal symptoms that can last up to a month. Therefore, patients are advised to taper off Suboxone slowly under the guidance of a medical provider to minimize withdrawal severity and ease symptoms [1].

Most individuals experience buprenorphine’s effects for almost the whole day, so sublingual Suboxone is typically taken about once per day. However, some individuals may be advised to take it every other day, divide the dose up to smaller doses, or take it two to three times daily based on individual needs [1].

Acute Withdrawal

Acute withdrawal from buprenorphine, a component of Suboxone, can last up to a month, compared to heroin withdrawal symptoms that typically last around a week. The severity of withdrawal during Suboxone tapering can be reduced significantly by working with a medical provider to taper slowly over weeks to months [1]. This underscores the importance of closely following medical advice when undergoing Suboxone treatment.

Medical Guidance

Regular medical guidance is essential throughout the course of Suboxone treatment. The duration of Suboxone's effects varies from person to person due to differences in metabolism, so following the doctor's instructions is crucial. Suboxone should never be mixed with alcohol as it can have fatal consequences, causing respiratory suppression, hypoxia, coma, and brain damage [5].

In conclusion, while Suboxone can be highly effective in treating opioid addiction, it's important to manage the treatment process carefully to avoid adverse effects. By understanding and implementing the tapering process, recognizing and managing acute withdrawal symptoms, and seeking regular medical guidance, patients can safely and effectively use Suboxone as part of their recovery journey.








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